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Publicaties en Voordrachten

Publicaties

1. Eslami S, de Keizer NF, de Jonge E, Bosman RJ, Schultz MJ, Spronk P, Abu-Hanna A.
   Implementing Glucose Control in Intensive Care - A Multicenter trial Using Statistical Process Control. Intensive Care Med. 2010 Jun 9. [Epub ahead of print] PMID: 20533024
2. Kuijsten HAJM, Brinkman S, Meynaar IA, Spronk PE., van der Spoel JI, Bosman RJ, de Keizer NF, AbuHanna A, de Lange DW.
   Hospital mortality is associated with ICU admission time. Intensive Care Med. 2010 Jun 15. [Epub ahead of print] PMID: 20549184
3. van der Veer SN, de Keizer NF, Ravelli ACJ, Tenkink S, Jager KJ.
   Improving quality of care. A systematic review on how medical registries provide information feedback to health care providers. Int J Med Inform. 2010 May;79(5):305-23.
4. MLG de Vos, SN van der Veer, WC Graafmans, NF de Keizer, KJ Jager, GP Westert, PHJ van der Voort.
   Implementing quality indicators in ICUs: exploring barriers to and facilitators of behaviour change. Implementation Science 2010 accepted
5. Bakhshi-Raiez F; Ahmadian L; Cornet R; de Jonge E; de Keizer N.
   Construction of an Interface Terminology on SNOMED CT: Generic Approach and its Application in Intensive Care. Methods of Information in Medicine 2010 accepted
6. Peelen L, de Keizer NF, de Jonge E, Bosman RJ, Abu-Hanna A, Peek N.
   Using hierarchical dynamic Bayesian networks to investigate dynamics of organ failure in patients in the Intensive Care Unit. Unit. J Biomed Inform. 2010:43(2):273-86
7. DW de lange, J Dusseljee, S Brinkman, G van Berkel, R van Maanen, RJ Bosman, H Joore, NF de Keizer, PHJ van de Voort, R de Waal, RMJ Wesselink, E de Jonge.
   Severity of illness and outcome in ICU patients in the Netherlands: results from the NICE registry 2006-2007 Neth J Crit Care 2009 Feb 13:16:22
8. PHJ van der Voort, F Bakhshi-raiez, DW de lange, rJ Bosman, E de Jonge, H Joore, r de Waal, rMJ Wesselink, G van Berkel, r van Maanen, NF de Keizer
   Trends in time; Results from the NICE registry. Neth J Crit Care 2009 Feb 13(1):8-15
9. de Keizer NF, Bakhshi-Raiez F, de Jonge E, Cornet R.
   Post-coordination in practice: evaluating compositional terminological-system-based registration of ICU reasons for admission. Int. J.Med. Inform. 2008;77: 828-835.
10. Minne L, Abu-Hanna A, de Jonge E.
    Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review. Crit Care. 2008;12(6):R161. Epub 2008 Dec 17.
11. de Jonge E, Peelen L, Keijzers PJ, Joore JCA, de Lange D, van der Voort PHJ, Bosman RJ, de Waal RAL, Wesselink R, de Keizer NF.
    Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated ICU patients. Crit Care 2008 Dec 10;12(6):R156
12. Nannings B, Abu-Hanna A, de Jonge E.
    Applying PRIM (Patient Rule Induction Method) and logistic regression for selecting high-risk subgroups in very elderly ICU patients. Int J Med Inform. 2008 Apr;77(4):272-9. Epub 2007 Jul 23.
13. Wunsch H, Angus DC, Harrison DA, Collange O, Fowler R, Hoste EAJ, de Keizer NF, Kersten A, Linde-Zwirble WT, Sandiumenge A, Rowan KM.
    Variation in critical care services across North America and Western Europe. Crit Care Med 2008; 36:...
14. Bahkshi-Raiez F, Peek NB, Bosman RJ, de Jonge E, de Keizer NF.
    The impact of different prognostic models and their customization on institutional comparison of Intensive Care Units. Crit Care Med 2007
15. Peek N, Arts DGT, Bosman RJ, van der Voort PHJ, de Keizer NF.
    External validation of prognostic models for critically ill patients requires substantial sample sizes. J Clin Epidemiol. 2007 May;60(5):491-501.
16. Peelen LM, de Keizer NF, Peek NB, Scheffer GJ, van der Voort P, de Jonge E.
    The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study. Crit Care. 2007 Mar 22;11(2):R40
17. de Rooij SE, Abu-Hanna A, Levi M, de Jonge E.
    Identification of high-risk subgroups in very elderly intensive care unit patients. Crit Care.2007;11(2):R33.
Peelen LM, Peek NB, de Jonge E, Scheffer GJ, de Keizer NF.
The use of a registry database in clinical trial design: assessing the influence of entry criteria on statistical power and trial costs. Int J Med Inform 2007;76:176-184.
18. Peelen L, de Keizer NF, Peek N, Bosman RJ, Scheffer GJ, de Jonge E.
    Influence of entry criteria on mortality risk and number of eligible patients in recent studies on severe sepsis. Crit Care Med. 2005 Oct; 33(10):2178-2183.
19. Arts DG, de Keizer NF, Vroom MB, de Jonge E.
    Reliability and accuracy of Sequential Organ Failure Assessment (SOFA) scoring. Crit Care Med. 2005 Sep;33(9):1988-1993
20. Arts DG, Cornet R, de Jonge E, de Keizer NF.
    Methods for evaluation of Medical Terminological Systems. A literature review and a case study. Methods Inf Med 2005; 44:616-25
21. De Jonge E, Bosman RJ, van der Voort PH, Korsten HH, Scheffer GJ, De Keizer NF.
    [Intensive care medicine in the Netherlands, 1997-2001. I. Patient population and treatment outcome]. Ned.Tijdschr.Geneeskd. 2003;147:1013-17.
22. Bosman RJ, De Jonge E, De Keizer NF, Joore JC, van der Voort PH, Scheffer GJ.
    [Intensive care medicine in the Netherlands, 1997-2001. II. Changes over time and differences between hospitals]. Ned.Tijdschr.Geneeskd. 2003;147:1018-24.
23. Arts DG, Bosman RJ, De Jonge E, Joore JC, De Keizer NF.
    Training in data definitions improves quality of intensive care data. Crit Care 2003;7:179-84.
24. Arts DG, Cornet R, De Jonge E, De Keizer NF.
    Comparison of methods for evaluation of medical terminological systems. Proc.AMIA.Symp. 2003;779.
25. Abu-Hanna A, De Keizer NF.
    Integrating Classification Trees with local regression in Intensive Care prognosis. Artif Intell Med 2003;29:5-23.
26. Arts DGT, De Keizer NF, De Jonge E.
    Kwaliteitswaarborging in medische registraties. Informatie & Zorg 2002;31:17-21.
27. Arts DG, De Keizer NF, Scheffer GJ.
    Defining and improving data quality in medical registries: a literature review, case study, and generic framework. J.Am.Med.Inform.Assoc. 2002;9:600-11.
28. Arts D, de Keizer N, Scheffer GJ, De Jonge E.
    Quality of data collected for severity of illness scores in the Dutch National Intensive Care Evaluation (NICE) registry. Intensive Care Med. 2002;28:656-59.
29. De Keizer NF, Bonsel GJ, Goldfad C, Rowan KM.
    The added value that increasing levels of diagnostic information provide in prognostic models to estimate hospital mortality for adult intensive care patients. Intensive Care Med. 2000;26:577-84.
30. De Keizer NF, Abu-Hanna A, Cornet R, Zwetsloot-Schonk JH, Stoutenbeek CP.
    Analysis and design of an ontology for intensive care diagnoses. Methods Inf.Med. 1999;38:102-12.
31. De Keizer NF, Bosman RJ, Joore JC, Korsten HH, Langenberg CJM, Scheffer GJ et al.
    De betekenis van het PDMS in het primaire zorgproces en in evaluatie onderzoek van Intensive Care. Informatie & Zorg 1999.
32. De Keizer NF, Bosman RJ, Joore JCA, Korsten HHM, Langenberg CJM, Scheffer GJ et al.
    Landelijk kwaliteitssysteem voor intensive care. Medisch Contact 1999;54:276-79.
33. De Keizer NF, Scheffer GJ, Bosman RJ.
    Het NICE-project: naar nationale kwaliteitsborging van IC-geneeskunde. Ned.Tijdschr.Intensive Care 1999;14:187-88.
34. Bosman RJ, De Keizer NF.
    Prognostic performance and customization of the SAPS II. Intensive Care Med. 1999;25:878-79.
35. De Keizer NF, Stoutenbeek CP, Hanneman LA, De Jonge E.
    An evaluation of Patient Data Management Systems in Dutch Intensive Care. Intensive Care Med. 1998;24:167-71.
36. Bosman RJ, Oudemans van Straaten HM, Zandstra DF.
    The use of intensive care information systems alters outcome prediction. Intensive Care Med. 1998;24:953-58.

Gepubliceerd als abstract

1. Weerheijm, D., Dusseljee, J., De Keizer, N., De Jonge, E., Van der Hoeve, H., and Pickkers, P.
   The protective effect of obesity on ICU mortality is mediated by an altered immune response. Netherlands Journal of Critical Care, abstract # 47, December 2007.
2. C.M.A. Bles, L. Peelen, J.G. van der Hoeven, P.Picckers.
   `Length of stay of Intensive Care Unit patients: effects on outcome. Nederlandse Intensivisten Dagen 2008, abstract # 42. Ede, February 2008.
3. L. Peelen, N. Peek, N.F. de Keizer, R.J.Bosman.
   Stratified analysis of multivariate state changes in critically ill patients. Proceedings BENELEARN conference 2007 (pp 61-68), Amsterdam, The Netherlands, May 2007.
4. P. Keijzers, L. Peelen, R.J. Bosman, N.F. de Keizer, E. de Jonge.
   A high FiO2 and a high PaO2 are risk factors for in-hospital mortality in ICU-patients, independent of severity of pulmonary dysfunction and severity of illness. Nederlandse Intensivisten Dagen 2007, abstract #33. Ede, January 2007.
5. S. Schlobach, M. Klein, L. Peelen.
   Description Logics with approximate definitions. Precise modeling of vague concepts. Proceedings International Joint Conferences on Artificial Intelligence (IJCAI) 2007 (pp 557-562), Hyderabad, India, January 2007.
6. L. Peelen, N. Peek, R.J. Bosman.
   Describing scenarios for disease episodes and estimating their probability: a new approach with an application in Intensive Care. Working notes of the workshop on Intelligent Data Analysis in BioMedicine and Pharmacology (IDAMAP-06). Verona, August 2006, pp77-82.
7. L. Peelen, N. Peek, N.F. de Keizer, E. de Jonge, G.J. Scheffer.
   Modeling changes in organ failure for patients at the Intensive Care Unit. Proceedings of the Medical Informatics Europe (MIE) conference, 2006. Stud Health Technol Inform. 2006;124:555-60. PMID: 17108576
8. L. Peelen, C.H.K. Tan, N. Peek.
   Instance-based prognosis in Intensive Care using severity-of-illness scores. Annual Conference of the European Society on Computing and Technology in Anaesthesia and Intensive Care (ESCTAIC), Aalborg, Denmark, September 2005
9. L. Peelen, N. Peek, N.F. de Keizer, E. de Jonge.
   Investigating the effect of differences in entry criteria on trial populations: a method with an application in severe sepsis. Proceedings of the Medical Informatics Europe (MIE) conference 2005. Genève, August 2005. Stud Health Technol Inform. 2005; 116:1004-1009. PMID: 16160390
10. C. Tan, L. Peelen, N. Peek.
    Instance-based prognosis in Intensive Care using severity-of-illness scores. W orking notes of the workshop on Intelligent Data Analysis in BioMedicine and Pharmacology (IDAMAP-05). Aberdeen, July 2005, pp21-26.
11. R.J. Bosman, L.M. Peelen, E. de Jonge.
    Body Mass Index (BMI) and hospital mortality. Intensive Care Medicine, 2004; 30 (Suppl) p S9 #20.
12. L. Peelen and N. Peek.
    Comparing entry criteria in severe sepsis trials: a Bayesian approach. Proceedings of the 25th Annual Congress of the International Society of Clinical Biostatistics, Leiden, August 2004, p183.
13. L. Peelen, N. Peek, A. Zwinderman.
    Statistical methods to compare different definitions of disease with an application to severe sepsis. Working notes of the joint workshop on Intelligent Data Analysis in Medicine and Pharmacology (IDAMAP-03) and Knowledge-Based Information Management in Anaesthesia and Intensive Care (KBM-AIC), Cyprus October 2003, pp13-16.
14. L.M. Peelen, N.F. de Keizer, N.Peek, E. de Jonge, R.J. Bosman, G.J. Scheffer.
    Different definitions for severe sepsis yield significantly different study populations. Intensive Care Medicine, 2003; 29(Suppl) p74, # 272.
15. Bosman, R. J., Joore, J. C., De Jonge, E., and de Keizer, N.
    Intensive Care Information Systems improve quality of physician documantation. Intensive Care Med. 29(supp1), S39. 2003. Ref Type: Abstract
16. Peelen, L. M., de Keizer, N., Peek, N. B., De Jonge, E., Bosman, R. J., and Scheffer, G. J.
    Different definitions in sepsis trials yield significantly different study populations. Intensive Care Med. 29(supp1), S74. 2003. Ref Type: Abstract
17. Bosman, R. J., Joore, J. C., De Jonge, E., and de Keizer, N.
    Differences in efficacy between hospitals in treating pneumonia. Intensive Care Med. 29(supp1), S39. 2003. Ref Type: Abstract
18. Bosman, R. J. and de Keizer, N.
    Differences in hospital mortality paterns depending on weekday of ICU discharge. Intensive Care Med. 26(supp3), S237. 2000. Ref Type: Abstract
19. Arts, D., Bosman, R. J., de Keizer, N., and De Jonge, E.
    Training improves quality of prognostic scoring data. Intensive Care Med. 26(supp3), S260. 2000. Ref Type: Abstract
20. Bosman, R. J. and De Keizer, N. F.
    APACHE II and SAPS II in cardiosurgical patients. Intensive Care Med. 25(supp), S13. 1999. Ref Type: Abstract

Dissertaties

1. Peelen LM.
   Sepsis in Intensive Care. Modeling disease definitions and dynamics of disease using medical registry data. Studies in ICU patients with severe sepsis. 10-11-2009
2. Arts, D.G.T.
   Information for Intensive Care Evaluation. 24-5-2005. University of Amsterdam. Ref Type: Thesis/Dissertation
3. De Keizer, N. F.
   An infrastucture for quality assessment in Intensive Care. 14-4-2000. University of Amsterdam. Ref Type: Thesis/Dissertation

Voordrachten

1. De Keizer NF
   A national registry to improve quality of critical care units Annual conference of the Japanese Society of Intensive Care Osaka, Japan February 2009
2. De Keizer, NF
   Gender difference in Intensive Care. Symposium "Hormones in Intensive Care", Vrije Universiteit Amsterdam, October 2008.
3. Van der Voort PHJ, de Keizer NF
   How to improve the quality of care Symposium "Frontiers in critical care medicine 1983-2008", November 2008 OLVG Amsterdam.
4. De Jonge, E.
   Risico's van kwaliteitsindicatoren. 2005. Ede. Intensivistendagen. 25-2-2005. Ref Type: Conference Proceeding
5. Peelen, L. M. and Peek, N. B.
   Comparing entry criteria in severe sepsis trials: a Bayesian approach. 2004. Leiden. Proceedings of the 25th Annual Symposium of the International Society of Clinical Biostatistics. 2004. Ref Type: Conference Proceeding
6. Bosman, R. J.
   Iedere IC moet meedoen met NICE. 2004. Utrecht. VentiCare. 28-5-2004. Ref Type: Conference Proceeding
7. Peelen, L. M., Zwinderman, A., and Peek, N. B.
   Statistical methods to compare different definitions of disease with an application to severe sepsis. 2003. Cyprus. Working notes of the joint workshop on Intelligent Data Analysis in Medicine and Pharmacology (IDAMAP) and Knowledge-Based Information Management in Anaesthesia and Intensive Care (KBM-AIC). 2003. Ref Type: Conference Proceeding
8. Peelen, L. M., de Keizer, N., Peek, N. B., De Jonge, E., Bosman, R. J., and Scheffer, G. J.
   Different definitions for severe sepsis yield significantly different study populations. 2003. Amsterdam. Eur.Soc.Intensive Care Med. 2003. Ref Type: Conference Proceeding
9. De Jonge, E.
   Wat wil de oude patient en wat zijn de resultaten van behandeling. 2003. Amsterdam. Openingssymposium IC Academisch Medisch Centrum. 31-10-2003. Ref Type: Conference Proceeding
10. De Jonge, E.
    Resultaten in NICE. 2003. Groningen. Intensive Care Wetenschapssymposium. 23-1-2003. Ref Type: Conference Proceeding
11. De Jonge, E.
    Zeer oude patienten op de Intebnsive Care. 2003. Utrecht. Venticare. 22-5-2003. Ref Type: Conference Proceeding
12. Bosman, R. J.
    Intensive Care na hartchirurgie; gegevens uit de NICE registratie. 2003. Arnhem. Congres Ned.Ver.Anesthesiologie. 25-9-2003. Ref Type: Conference Proceeding
13. de Keizer, N.
    NICE, opzet van de database. 2002. Arnhem. Nederlandse Intensivistendagen. 7-2-2002. Ref Type: Conference Proceeding
14. Nannings, B., Abu-Hanna, A., and de Keizer, N.
    Rol van diagnosen in prognose. Noordwijkerhout. Zorg-ICT Congres MIC2001. 23-11-2001. Ref Type: Conference Proceeding
15. de Keizer, N.
    Nationale Intensive Care Evaluatie, resultaten uit de database. 2001. Arnhem. Nederlandse Intensivistendagen. 15-2-2001. Ref Type: Conference Proceeding
16. De Jonge, E.
    NICE: Dutch evaluation of Intensive Care. 2001. Geneva. Annual Congress of Eur.Soc.Intensive Care Med. 2001. Ref Type: Conference Proceeding
17. Arts, D., de Keizer, N., and De Jonge, E.
    Kwaliteitswaarborging in medische registraties. 2001. Noordwijkerhout. Zorg-ICT congres MIC 2001. 23-11-2001. Ref Type: Conference Proceeding
18. Arts, D., de Keizer, N., and De Jonge, E.
    Data quality measurement and assurance in medical registries. 2001. London. 10th World Congress on Medical Informatics. 2001. Ref Type: Conference Proceeding
19. Abu-Hanna, A. and de Keizer, N.
    A classification tree hybrid method for studying prognostic models in intensive care. 2001. Lissabon. Proceedings Artificial Intelligence in Medicine. 2001. Ref Type: Conference Proceeding
20. de Keizer, N., Abu-Hanna, A., and Cornet, R.
    Design and evaluation of DICE, a teminological system for intensive care diagnoses. 2000. Hannover. MIE2000. 29-9-2000. Ref Type: Conference Proceeding
21. de Keizer, N.
    Automatiseringsontwikkelingen. 2000. Amsterdam. AMC/NVIC symposium "Intensive Care 2010". 31-5-2000. Ref Type: Conference Proceeding
22. de Keizer, N.
    NICE: succesfactoren, uitdagingen en toekomstplannen. 2000. Amsterdam. Symposium Medische Informatiekunde en kwaliteit van zorg. 14-4-2000. Ref Type: Conference Proceeding
23. Bosman, R. J.
    Gebruik van bestaande informatiebronnen voor evaluatie-onderzoek; PDMS en ZIS als extractiebron. 2000. Symposium Medische informatiekunde en kwaliteit van zorg. 14-4-2000. Ref Type: Conference Proceeding
24. Bosman, R. J. and de Keizer, N.
    Differences in hospital mortality patterns depending on weekday of ICU discharge. 2000. Rome. 13th annual congress of Eur.Soc.Intensive Care Med. 2-10-2000. Ref Type: Conference Proceeding
25. Bosman, R. J.
    De landelijke IC database. 2000. Arnhem. Nederlandse Intensivistendagen. 9-2-2000. Ref Type: Conference Proceeding
26. Bosman, R. J. and de Keizer, N.
    APACHE II and SAPS II in cardiosurgical patients. 1999. Berlin. 12th annual congress European Society Intensive Care Medicine. 4-10-1999. Ref Type: Conference Proceeding
27. de Keizer, N., Cornet, R., Abu-Hanna, A., Zwetsloot-Schonk, J. H., and Stoutenbeek, C. P.
    An Intensiev care diagnosis classification supporting the care process and quality assurance. 1998. Seoul. Medinfo'98. Ref Type: Conference Proceeding
28. de Keizer, N.
    An infrastructure and diagnostic classification for National Intensive Care Evaluation. 1998. ISQua98. 6-10-1998. Ref Type: Conference Proceeding
29. de Keizer, N.
    Landelijke database Intensive Care. 1997. Eindhoven. Symposium Kwaliteitswet op de Intensive Care. 25-6-1997. Ref Type: Conference Proceeding
30. de Keizer, N.
    Informatiesystemen voor de Intensive Care. 1997. Nederlandse Vereniging voor Anesthesiologie; sectie Intensive Care. 8-12-1997. Ref Type: Conference Proceeding
31. Binnenkade, J. M., de Keizer, N., Stoutenbeek, C. P., and De Haan, R. J.
    Registration of ICU nursing care in Dutch hospitals. 1997. 2nd International Conference Scientific Basis of Health Services. 8-10-1997. Ref Type: Conference Proceeding
32. de Keizer, N.
    PDMS evaluatie aan de hand van de landelijke specificaties. 1996. Ede. Topics in Intensive Care. 6-11-1996. Ref Type: Conference Proceeding
33. de Keizer, N.
    Information from the Dutch national database. 1996. Ede. Topics in Intensive Care. 6-11-1996. Ref Type: Conference Proceeding
34. de Keizer, N.
    NICE: op weg naar een kwaliteitssysteem in de Intensive Care. 1996. Brussel. MIC. 15-11-1996. Ref Type: Conference Proceeding

De Nationale Intensive Care Evaluatie omvat een continue en complete registratie van alle opgenomen patiënten in deelnemende intensive cares voor het monitoren en bevorderen van de kwaliteit van zorg. NICE is een stichting zonder winstoogmerk, opgericht door de beroepsgroep (intensivisten). Het beheer van de registratie vindt plaats op de afdeling Klinische Informatiekunde (AMC) en valt onder het Kwaliteitsmanagementsysteem Medische Registratie dat gecertificeerd is volgens de ISO 9001:2000 norm.